Arsene Wenger says Alexis has suffered an abdominal strain and will not feature in the Gunners opening games of the new Premier League campaign.
The Chile international only returned to first team training last week after an extended break after participating in the Confederations Cup.
It now appears he’s picked up a problem in training meaning his pre-season preparations have suffered a setback.
“He has a little abdominal strain,” Wenger told his first press conference of the new season.
“He caught it on Sunday morning before coming to Wembley. He had a scan two days ago and he’s out for a while. I don’t know if it’s for two weeks or one more week. I think he will not play at Stoke [on 19 August].
“Always for us, Alexis Sanchez, is a loss. We have the other players prepared in pre-season and it can happen. I don’t think I would have included him on Friday night, I wouldn’t have started him.
“He’s been focused. Of course, when you have treatment on the medical bench, it’s not easy.”
The boss also confirmed that there are doubts over Mesut Ozil and Aaron Ramsey, who both missed Sunday’s victory over Chelsea in the Community Shield, and Per Mertesacker, who suffered a bad cut above his eye in the game. Laurent Koscielny is suspended for two games due to the red card picked up on the final day of last season.
Francis Coquelin (ankle ligament damage) and Gabriel (knee) are also set to miss out.
We’ll go out on a limb and guess that those players whose futures at the club are in doubt will also miss out, that includes Jack Wilshere, Calum Chambers, Lucas Perez, Kieran Gibbs and Mathieu Debuchy.